Breakthrough solutions and Cost-Disruptive innovations
Biotechnology Industrial Research Assistance council
📌 About the Event
This Request for Proposal (RFP) represents a major funding opportunity for Indian researchers and innovators to develop high-tech, low-cost medical diagnostics. Jointly supported by the Government of India (DBT/BIRAC) and the Bill & Melinda Gates Foundation, the program targets “cost-disruptive” solutions for the country’s most pressing infectious diseases.
Below is a structured breakdown of the call, its technical requirements, and the financial categories.
ℹ️ Key Details & Deadlines
- Call Opens: 12th May 2026
- Submission Deadline: 1st July 2026, 2:00 PM IST
- Focus: Breakthrough, high-risk, high-reward innovations in screening and diagnosis.
- Eligibility: Exclusive to Indian researchers/entities (Companies, LLPs, Academic Institutions, and NGOs).
🎯 The “Grand Challenge”: Cost & Performance Targets
The defining metric of this RFP is the cost-disruptive nature of the solution:
- Target Price: Approximately ₹100 ($1 USD) per test.
- Target Format: Point-of-care (near the patient), minimal infrastructure, and “software-defined” or AI-enabled diagnostics.
- Pathway: Moving away from expensive, centralized lab tests toward “near-zero marginal cost” per person screened.
🔬 Priority Disease Areas
1. Tuberculosis (TB)
Focus on non-sputum samples (breath, skin, etc.) and symptom-agnostic screening to find asymptomatic cases in the community.
2. Emerging Pathogens
Developing “reconfigurable” platforms that can quickly adapt to new viruses (like COVID-19 variants or new outbreaks) without needing a full redesign.
3. Syndromic Panels
Tools that can test for multiple diseases at once (e.g., Dengue, Malaria, Typhoid) from a single sample to avoid diagnostic delays in febrile illness.
4. Enteric Infections
Rapid, near-patient tests for Typhoid (Salmonella Typhi) and pediatric diarrhea, prioritizing the differentiation between bacterial and viral causes to prevent antibiotic misuse.
💰 Funding Categories & TRL Levels
The program is split into two tracks based on the Technology Readiness Level (TRL):
| Category | TRL Range | Max Budget | Duration | Focus |
| Exploratory | TRL 2 – 4 | ₹50 Lakh ($55k) | 12 Months | Proving the concept and early lab data. |
| Solution | TRL 4+ | ₹2 Crore ($200k) | 18 Months |